MEDICINE FOR WEIGHT GAIN
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๐ Medicines for Weight Gain
(to be considered under physician supervision)
1. Appetite Stimulants
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Cyproheptadine – Antihistamine with appetite stimulant effect, sometimes used in underweight patients.
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Megestrol acetate – Used in cachexia due to cancer or chronic illness.
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Dronabinol (cannabinoid) – For AIDS/cancer-related anorexia.
2. Anabolic / Nutritional Support
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Anabolic steroids (Oxandrolone, Nandrolone) – Used in specific cases (burns, severe muscle wasting). Risk of liver/cardiac side effects → not for general use.
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Nutritional supplements (protein powders, high-calorie formulas, omega-3, multivitamins).
3. Hormonal Therapy (only if deficiency proven)
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Thyroxine adjustment – If hypothyroidism undertreated, weight gain may be natural with correction.
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Insulin – In Type 1 DM patients, correct therapy helps restore weight.
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Growth hormone – In GH deficiency in children/adolescents.
4. Psychiatric Indications
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Some antidepressants (Mirtazapine, Amitriptyline) and antipsychotics (Olanzapine, Clozapine) cause weight gain → sometimes used in patients with severe undernutrition due to psychiatric illness.
⚠️ Important Notes:
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These medicines are not recommended for cosmetic weight gain.
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First-line: nutritional counseling, high-calorie diet, exercise (strength training), treatment of underlying disease (TB, malabsorption, thyroid, diabetes, depression).
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Medicines are used mainly in disease-related weight loss (cachexia, HIV, cancer, severe malnutrition, psychiatric illness).
Mirtazapine is an antidepressant (Noradrenergic and Specific Serotonergic Antidepressant – NaSSA) often used for major depressive disorder, and it also has the side effect of increased appetite and weight gain.
๐ Common Trade Names of Mirtazapine
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Remeron – Original brand (by Organon/Schering-Plough, available in many countries)
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Mirtaz – (Sun Pharma, India)
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Mirnite – (Intas, India)
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Mirzaten – (International markets)
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Avanza – (Some European countries & Australia)
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Zispin – (UK, Ireland)
๐ Available strengths: 7.5 mg, 15 mg, 30 mg, 45 mg tablets
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