4 Drug-Induced Hepatitis (DIH) A patient-education oriented, clinically practical overview What is Drug-Induced Hepatitis? Drug-Induced Hepatitis is liver inflammation caused by medicines, herbal products, or toxins . The liver is the main organ for drug metabolism, and some drugs can injure liver cells directly or through immune reactions. Hindi: दवा से होने वाला हेपेटाइटिस वह स्थिति है जिसमें दवाओं या हर्बल उत्पादों के कारण लिवर में सूजन आ जाती है। Common Drugs Causing Hepatitis Painkillers: Paracetamol (especially overdose) Anti-TB drugs: Isoniazid, Rifampicin, Pyrazinamide Antibiotics: Amoxicillin-clavulanate, Erythromycin Antiepileptics: Phenytoin, Valproate Statins Herbal / Ayurvedic / Unregulated supplements ⚠️ “Natural” does NOT always mean safe for the liver. Types of Drug-Induced Liver Injury Hepatocellular – Raised ALT/AST Cholestatic – Raised ALP, Bilirubin Mixed Pattern Symptoms Fatigue, weakness Loss of appetite, nausea Yellow eyes/skin (jaundice) Dark urine,...
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